eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
4/2012
vol. 7
 
Share:
Share:
abstract:
Original paper

A study on the use of positron emission computed tomography analysis in recurrent colorectal cancer

Wojciech Zegarski
,
Bogdan Małkowski
,
Ewa Śrutek
,
Michał Klag
,
Iwona Głowacka

Prz Gastroenterol 2012; 7 (4): 203–208
Online publish date: 2012/09/23
View full text Get citation
 
PlumX metrics:
Introduction: Colorectal cancer is a common neoplasm in Europe and the United States. Even after apparently curative resection, recurrences occur in one-third of patients, usually within the first 2 to 3 years after the surgery.

Aim: Investigation the role of 18-fluorodeoxyglucose positron emission tomography/computed tomography (18-FDG PET/CT) in detection of recurrent colorectal cancer.

Material and methods: A retrospective analysis of 75 tumours from 59 patients with recurrent colorectal carcinoma was made.

Results: Detecting recurrent colorectal cancer FDG PET/CT revealed 92% sensitivity. PET/CT correctly identified 69 of 75 tumours. Negative PET/CT results of the examination depend on necrotic changes occurring in them (p < 0.01). SUVmax in tumours without necrotic changes was indeed statistically higher than in tumours with necrotic changes (p < 0.01). SUVmax in tumours located in the liver is indeed statistically higher than in tumours located in lungs (p < 0.05). A correlation between SUVmax of the tumour and age of the patients and the maximum dimension of the tumour was not found

(p < 0.05).

Conclusions: This study demonstrates that PET/CT is of high sensitivity. We conclude that FDG PET/CT is a powerful diagnostic imaging method, which has ability to improve accurate detection of recurrent colorectal cancer. The limitations of PET/CT are related to cellularity of the tumours. It is necessary to continue the study on correlation between SUV and molecular factors of tumours.
keywords:

olorectal cancer, recurrent, positron emission tomography/computed tomography analysis

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.