eISSN: 2391-6052
ISSN: 2353-3854
Alergologia Polska - Polish Journal of Allergology
Bieżący numer Archiwum Artykuły zaakceptowane O czasopiśmie Suplementy Zeszyty specjalne Rada naukowa Bazy indeksacyjne Prenumerata Kontakt Zasady publikacji prac Opłaty publikacyjne Standardy etyczne i procedury
Panel Redakcyjny
Zgłaszanie i recenzowanie prac online
3/2022
vol. 9
 
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Artykuł oryginalny

Ocena jakości życia pacjentów z alergią na pyłki przed kursem i po kursie immunoterapii podjęzykowej

Svitlana Zubchenko
1
,
Stepan Maruniak
2

  1. Department of Clinical Immunology and Allergology, Danylo Halytsky Lviv National Medical University, Lviv, Ukraine
  2. Department of Anesthesiology and Intensive Care, Shupyk National Medical Academy of Post-Graduate Education, Kyiv, Ukraine
Alergologia Polska – Polish Journal of Allergology 2022; 9, 3: 205–210
Data publikacji online: 2022/09/07
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Wstęp
Introduction: The presence of clinical symptoms significantly deteriorates quality of life (QOL) of patients with pollen allergy and requires proper allergy immunotherapy. Aim: To analyze QOL of patients with allergy to weed pollen before and after sublingual immunotherapy (SLIT) based on a MiniRQLQ questionnaire.

Materiał i metody
Totally, 485 individuals, 24 ±4.5 years old were examined. Clinical diagnosis of AR was made according to ARIA criteria (2014). SPT to standard inhaled allergens (Diater Laboratorios, Spain), total serum and specific immunoglobulins IgE, IFA, type-specific components of allergens, immunofluorescent method ImmunoCAP (“Phadia AB”, Swiss) were determined. Analysis of quality of life was performed based on a MiniRQLQ questionnaire.

Wyniki
Among patients of the Lviv region with pollen allergy, the most commonly detected positive SPTs were to Artemisia – in 62.3%, less to Ambrosia – 13.9% of individuals, combined sensitization – 23.8% of patients. Among them, genuine allergy to Artemisia was confirmed in 88.1%, to Ambrosia – 88.2% of individuals, co-sensitization – in 21 patients. According to the results of molecular investigations, SLIT was performed for 69.6% of patients (1st group), and 30.4% of individuals were treated symptomatically (2nd group). Based on the MiniRQLQ questionnaire, it was revealed that QOL indices in patients with pollen allergy, who underwent SLIT, were reliably lower after the first and the second years of treatment compared to the indices before SLIT. Reliable changes were not detected in patients of the second group.

Wnioski
Improvement of QOL indices after a course of SLIT indicated the efficacy of this treatment method in patients with pollen allergy.



Introduction
Introduction: The presence of clinical symptoms significantly deteriorates quality of life (QOL) of patients with pollen allergy and requires proper allergy immunotherapy. Aim: To analyze QOL of patients with allergy to weed pollen before and after sublingual immunotherapy (SLIT) based on a MiniRQLQ questionnaire.

Material and methods
Totally, 485 individuals, 24 ±4.5 years old were examined. Clinical diagnosis of AR was made according to ARIA criteria (2014). SPT to standard inhaled allergens (Diater Laboratorios, Spain), total serum and specific immunoglobulins IgE, IFA, type-specific components of allergens, immunofluorescent method ImmunoCAP (“Phadia AB”, Swiss) were determined. Analysis of quality of life was performed based on a MiniRQLQ questionnaire.

Results
Among patients of the Lviv region with pollen allergy, the most commonly detected positive SPTs were to Artemisia – in 62.3%, less to Ambrosia – 13.9% of individuals, combined sensitization – 23.8% of patients. Among them, genuine allergy to Artemisia was confirmed in 88.1%, to Ambrosia – 88.2% of individuals, co-sensitization – in 21 patients. According to the results of molecular investigations, SLIT was performed for 69.6% of patients (1st group), and 30.4% of individuals were treated symptomatically (2nd group). Based on the MiniRQLQ questionnaire, it was revealed that QOL indices in patients with pollen allergy, who underwent SLIT, were reliably lower after the first and the second years of treatment compared to the indices before SLIT. Reliable changes were not detected in patients of the second group.

Conclusions
Improvement of QOL indices after a course of SLIT indicated the efficacy of this treatment method in patients with pollen allergy.

słowa kluczowe:

quality of life, allergic rhinitis, pollen allergy, sublingual allergy immunotherapy



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