eISSN: 1897-4317
ISSN: 1895-5770
Gastroenterology Review/Przegląd Gastroenterologiczny
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
5/2010
vol. 5
 
Share:
Share:
abstract:
Original paper

Serum C-reactive protein level does not correlate with Crohn’s Disease Activity Index

Maciej Kohut
,
Katarzyna Kozioł
,
Emilia Olek
,
Anna Koclęga
,
Marek Hartleb

Przegląd Gastroenterologiczny 2010; 5 (5): 274–278
Online publish date: 2010/11/15
View full text Get citation
 
PlumX metrics:
Introduction : Crohn’s Disease Activity Index (CDAI) is a conventional, but poorly validated estimate of severity of Crohn’s disease (CD). Similarly, the clinical significance of elevated levels of C-reactive protein (CRP) in CD patients is not well recognized. It is also unknown whether these two indices have similar informative value.
Aim : To investigate the correlation between serum CRP level and CDAI.
Material and methods : One hundred and forty-six patients (66 men and 80 women, mean age 37 ±12 years) with well established diagnosis of CD were included in the study. According to the admittance protocol in all patients the serum CRP was measured and all data necessary to calculate CDAI were collected.
Results : There was no significant correlation between CRP and CDAI either in the entire population or in subgroups selected on the basis of CD severity, site of bowel involvement, kind of ongoing pharmacological therapy, past surgery or body mass.
Conclusions : There is no correlation between serum CRP level and CDAI. These two indices reflect different aspects of CD severity.
keywords:

Crohn’s disease, C-reactive protein, disease activity

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.